Author

T. Zang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

P. D. Bieniasz· 4 shared A. J. Greaney· 1 shared A. Rockstroh· 1 shared A. Schiepers· 1 shared A. T. Fard· 1 shared A. Talebi· 1 shared B. L. J. Poad· 1 shared C. C. Nelson· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersMicrobiology

P. D. Bieniasz

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Molecular fate-mapping of serum antibodies reveals the effects of antigenic imprinting on repeated immunization

A. Schiepers, M. F. van 't Wout, A. J. Greaney, T. Zang, H. Muramatsu, P. J. Lin, Y. K. Tam, L. Mesin, T. N. Starr, P. D. Bieniasz, N. Pardi, J. D. Bloom, G. D. Victora

This study uses molecular fate-mapping to show that repeated immunization preferentially reuses initial B cell clones over recruiting new ones, with imprinting effects decreasing as antigenic distance increases.

bioRxiv · Aug 29, 2022 · PreprintImmunology

Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins

F. Zhang, T. Zang, E. M. Stevenson, X. Lei, D. C. Copertino, T. M. Mota, J. Boucau, W. F. Garcia-Beltran, R. B. F. Jones, P. D. Bieniasz

This study identifies ORF7a proteins from sarbecoviruses as inhibitors of MHC-I antigen presentation, with a single amino acid difference affecting their function.

bioRxiv · May 25, 2022Microbiology

Derivation and Characterization of an inositol phosphate-independent HIV-1

D. Poston, T. Zang, P. D. Bieniasz

This paper identifies an HIV-1 mutant that replicates without inositol hexaphosphate (IP6) and shows that the drug Bevirimat can functionally replace IP6 in certain conditions.

bioRxiv · Mar 1, 2021 · PreprintMicrobiology

Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer

K. D. Tousignant, A. Rockstroh, B. L. J. Poad, A. Talebi, R. R. S. Young, A. T. Fard, R. Gupta, T. Zang, C. Wang, M. L. Lehman, J. V. Swinnen, S. J. Blanksby, C. C. Nelson, M. C. Sadowski

This study identifies therapy-induced lipid uptake and remodeling as drivers of ferroptosis hypersensitivity in prostate cancer, offering new strategies to combat drug resistance.

bioRxiv · Jan 8, 2020Cancer Biology

Vesicular stomatitis virus transcription is inhibited by TRIM69 in the interferon-induced antiviral state

T. Kueck, L.-M. Bloyet, E. Cassella, T. Zang, F. Schmidt, V. Brusic, G. Tekes, O. Pornillos, S. Whelan, P. D. Bieniasz

This study identifies TRIM69 as an IFN-induced antiviral factor that inhibits VSVIND replication by targeting its phosphoprotein P through a novel transcriptional inhibition mechanism.

bioRxiv · Jun 27, 2019Microbiology

OPUS-CSF: A C-atom-based Scoring Function for Ranking Protein Structural Models

G. Xu, T. Ma, T. Zang, Q. Wang, J. Ma

OPUS-CSF is a C-atom-based scoring function that ranks protein structural models more effectively than existing methods, recognizing more native structures in decoy sets.

bioRxiv · Jul 18, 2017Biophysics