T. Kurihara

A rat model of cirrhosis with well-differentiated hepatocellular carcinoma induced by thioacetamide

This study develops a rat model of cirrhosis-induced hepatocellular carcinoma using thioacetamide, showing fibrosis, altered liver architecture, and increased AFP levels.

Human Induced Pluripotent Stem Cell based Hepatic-Modeling of Lipid metabolism associated TM6SF2 E167K variant

This study creates a human iPSC-derived hepatocyte model with the TM6SF2 E167K mutation to study its effects on lipid metabolism and MASLD.

The orientation of choroidal macrophage polarization significantly influences the development of myopia in murine models

This study shows that choroidal macrophage polarization direction affects myopia development in mice, with M1 macrophages promoting and M2 macrophages suppressing myopia.

Capsular polysaccharide-mediated protein loading onto extracellular membrane vesicles of a fish intestinal bacterium, Shewanella vesiculosa HM13

This study identifies that the cargo protein P49 is loaded onto extracellular membrane vesicles of Shewanella vesiculosa HM13 via interaction with capsular polysaccharide (CPS).

Low Temperature and High Hydrostatic Pressure Have Compounding Negative Effects on Marine Microbial Motility

This study investigates how low temperature and high pressure affect marine microbial motility, finding compounding negative effects on flagellar function and motility.

Identification of a Putative Sensor Protein Involved in Regulation of Vesicle Production by a Hypervesiculating Bacterium, Shewanella vesiculosa HM13

This study identifies HM1275 as a sensor protein regulating vesicle production and biofilm suppression in Shewanella vesiculosa HM13 in response to lysine.