Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling
T. L. Light, D. Brun, P. Guardado-Calvo, R. Pederzoli, A. Haouz, F. Neipel, F. A. Rey, K. Hristova, M. Backovic
This study identifies how HHV-8 uses molecular mimicry of ephrin ligands to bind EphA2, triggering signaling that facilitates viral entry and cytoskeleton remodeling.
bioRxiv · Mar 26, 2021Microbiology