Author

T. L. Street

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:deep learning· 2 Assay:long-read sequencing· 2 Assay:metagenomics· 2 Research Focus:variant calling· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

D. W. Eyre· 4 shared N. D. Sanderson· 4 shared A. J. Brent· 2 shared A. Taylor· 2 shared B. L. Atkins· 2 shared D. Crook· 2 shared D. Foster· 2 shared D. W. Crook· 2 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersMicrobiology

D. W. Eyre

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4 papers

Recent·Most cited

Optimizing DNA extraction methods for Nanopore sequencing of Neisseria gonorrhoeae direct from urine samples

T. L. Street, L. Barker, N. D. Sanderson, J. Kavanagh, S. Hoosdally, K. Cole, R. Newnham, M. Selvaratnam, M. Andersson, M. Llewelyn, J. O'Grady, D. W. Crook, D. W. Eyre

This study optimizes DNA extraction methods for Nanopore sequencing of Neisseria gonorrhoeae directly from urine samples to enable culture-free whole-genome reconstruction.

Journal of Clinical Microbiology · Feb 24, 2020Peer-reviewedMicrobiology

High precision Neisseria gonorrhoeae variant and antimicrobial resistance calling from metagenomic Nanopore sequencing

N. D. Sanderson, J. Swann, L. Barker, J. Kavanagh, S. Hoosdally, D. Crook, the GonFast Investigators Group, T. L. Street, D. W. Eyre

This study develops a workflow for high-precision variant and antimicrobial resistance calling from metagenomic Nanopore sequencing of Neisseria gonorrhoeae.

bioRxiv · Feb 7, 2020Microbiology

Real-time analysis of nanopore-based metagenomic sequencing from orthopaedic device infection

N. D. Sanderson, T. L. Street, D. Foster, J. Swann, B. L. Atkins, A. J. Brent, M. A. McNally, S. Oakley, A. Taylor, T. E. A. Peto, D. Crook, D. W. Eyre

This paper compares metagenomic sequencing using Illumina MiSeq and Oxford Nanopore MinION platforms for diagnosing prosthetic joint infections, demonstrating a real-time analysis pipeline for rapid bacterial detection.

bioRxiv · Nov 17, 2017Microbiology

Molecular diagnosis of orthopaedic device infection direct from sonication fluid by metagenomic sequencing

T. L. Street, N. D. Sanderson, B. L. Atkins, A. J. Brent, K. Cole, D. Foster, M. A. McNally, S. Oakley, L. Peto, A. Taylor, T. E. A. Peto, D. W. Crook, D. W. Eyre

This study shows metagenomic sequencing of sonication fluid can accurately diagnose prosthetic joint infections with high sensitivity and specificity.

bioRxiv · Mar 18, 2017Microbiology