Cancer BiologybioRxiv
Unlocking the potential of miR-19b in the regulation of temozolomide response in glioblastoma patients via targeting PPP2R5E, a subunit of the protein phosphatase 2A complex
E. Kashani, K. Hlavackova, S. Haemmig…·E. Vassella
This study identifies miR-19b's role in TMZ resistance in GBM by targeting PPP2R5E, showing that miR-19b attenuation enhances TMZ efficacy in cell lines and xenografts.
DOI 10.1038/s41416-026-03474-2