Therapeutic Targeting of 15-PGDH in Murine Idiopathic Pulmonary Fibrosis
J. N. P. Smith, M. D. Witkin, A. P. Jogasuria, K. F. Christo, T. M. Raffay, S. D. Markowitz, A. B. Desai
This study shows that inhibiting 15-PGDH with a small molecule reduces fibrosis and improves lung function in a mouse model of IPF.
bioRxiv · Dec 16, 2019Pathology