ImmunologybioRxivPreprint
Endothelial Caveolin-1 and CXCL10 promote transcellular migration of autoreactive T cells across the blood-brain barrier
T. N. Trevino, A. A. Almousawi, A. Ochoa-Raya…·S. E. Lutz
This study shows that Caveolin-1 in brain endothelial cells stores CXCL10 to facilitate transcellular migration of autoreactive T cells across the blood-brain barrier, reducing neuroinflammation in EAE.
DOI 10.1101/2022.11.15.516689