Author

T. P. Gosain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

R. Singh· 2 shared A. Anand· 1 shared A. Ganguly· 1 shared A. Kumar· 1 shared A. Lee· 1 shared A. Sharma· 1 shared A. Singh· 1 shared A. Singhal· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

R. Singh

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2 papers

Recent·Most cited

Structural and functional characterization of Rv0792c from Mycobacterium tuberculosis: identifying small molecule inhibitors against GntR protein.

N. K. Chauhan, A. Anand, A. Sharma, K. Dhiman, T. P. Gosain, P. Singh, E. Khan, A. Kumar, D. Sharma, A. Ganguly, T. K. Sharma, R. Singh

This study characterizes Rv0792c, a GntR homolog from M. tuberculosis, identifies small molecule inhibitors, and reveals its role in stress adaptation and virulence.

bioRxiv · Sep 17, 2021 · PreprintMicrobiology

Disulfiram inhibits M. tuberculosis growth by altering methionine pool, redox status and host-immune response

D. Chaudhary, M. Marzuki, A. Lee, R. Bouzeyen, A. Singh, T. P. Gosain, S. Kidwai, C. Grady, K. Tsotetsi, K. Chawla, F. Shihui, J. Lum, S. K. Gupta, N. Agarwal, L. Tsenova, , A. Singhal

This study identifies disulfiram as a novel inhibitor of Mtb's methionine biosynthesis, showing anti-tubercular effects through redox disruption and immune modulation.

bioRxiv · Sep 1, 2020 · PreprintMicrobiology