Author

M. Marzuki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Singhal· 4 shared A. Lee· 3 shared B. Lee· 3 shared J. Lum· 3 shared A. Singh· 2 shared D. Kumar· 2 shared F. Shihui· 2 shared P. Kumar· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersImmunology

A. Singhal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A mitochondrial quality control mechanism reverses the phagosome maturation arrest caused by Mycobacterium tuberculosis

S. Verma, S. Thakur, M. Das, R. D. Sharma, V. Yadav, P. Sharma, M. Marzuki, S. Foo, G. M. Piperno, M. Z. Khan, B. Mathew, M. Bajpai, J. S. Maras, S. Howland, S. Sarkar, , D. Kumar

This study identifies a mitochondrial quality control mechanism that reverses phagosome maturation arrest caused by Mycobacterium tuberculosis through RAB7 recruitment and lysosomal targeting.

bioRxiv · Dec 1, 2023 · PreprintCell Biology

Disulfiram inhibits M. tuberculosis growth by altering methionine pool, redox status and host-immune response

D. Chaudhary, M. Marzuki, A. Lee, R. Bouzeyen, A. Singh, T. P. Gosain, S. Kidwai, C. Grady, K. Tsotetsi, K. Chawla, F. Shihui, J. Lum, S. K. Gupta, N. Agarwal, L. Tsenova, , A. Singhal

This study identifies disulfiram as a novel inhibitor of Mtb's methionine biosynthesis, showing anti-tubercular effects through redox disruption and immune modulation.

bioRxiv · Sep 1, 2020 · PreprintMicrobiology

Metformin enhances anti-mycobacterial responses by educating immunometabolic circuits of CD8+ T cells

J. Bohme, N. Martinez, S. Li, A. Lee, M. Marzuki, A. Tizazu, D. Ackart, J. Frenkel, A. Todd, E. Lachmandas, J. Lum, F. Shihui, T. P. Ng, B. Lee, A. Larbi, , A. Singhal

This study shows metformin improves anti-mycobacterial responses by enhancing metabolic and functional properties of CD8+ T cells in mice and humans.

bioRxiv · Aug 26, 2020Immunology

Histone acetylome-wide association study of tuberculosis

R. C. H. del Rosario, J. Poschmann, P. Kumar, C. Y. Cheng, S. T. Ong, H. S. Hajan, D. Kumar, M. Marzuki, X. Lu, A. Lee, Y. Tang, C. B. E. Chee, C. Lim, B. Lee, J. Lum, , S. Prabhakar

This study conducts a histone acetylome-wide association study (HAWAS) of tuberculosis, identifying differentially acetylated loci and their association with immune phenotypes.

bioRxiv · May 21, 2019 · PreprintImmunology