Author

T. R. Donahue

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Ribas· 1 shared C. G. Radu· 1 shared E. R. Abt· 1 shared G. Abril-Rodriguez· 1 shared J. Czernin· 1 shared J. R. Capri· 1 shared S. Poddar· 1 shared T. M. Le· 1 shared

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2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Ribas

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintNov 4, 2019

Defective Nucleotide Catabolism Defines a Subset of Cancers Sensitive to Purine Nucleoside Phosphorylase Inhibition

E. R. Abt, V. Lok, T. M. Le…·C. G. Radu

This study identifies SAMHD1, dCK, and CDA as biomarkers for predicting sensitivity to PNP inhibitors in cancers, showing that PNP inhibition can target both hematological and solid tumors.

DOI 10.1101/810093

humanbulk RNA-seq

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