Author

S. Poddar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:plant (other)· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. Staskawicz· 3 shared J. Tanaka· 3 shared M.-J. Cho· 3 shared A. M. Owens· 1 shared A. Ribas· 1 shared A. van der Vaart· 1 shared B. Minkenberg· 1 shared B. T. Ugaz· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersPlant Biology

B. Staskawicz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Uracil-DNA glycosylase efficiency is modulated by substrate rigidity

P. B. Orndorff, S. Poddar, A. M. Owens, B. T. Ugaz, N. Kumari, S. Amin, W. D. Van Horn, A. van der Vaart, M. Levitus

This study shows that uracil-DNA glycosylase efficiency is determined by substrate flexibility, with more flexible DNA sequences showing higher enzyme activity.

bioRxiv · Aug 30, 2022Biophysics

Improvement of Gene Delivery and Mutation Efficiency in the CRISPR-Cas9 Wheat (Triticum aestivum L.) Genomics System via Biolistics

J. Tanaka, B. Minkenberg, S. Poddar, B. Staskawicz, M.-J. Cho

This study improves CRISPR-Cas9 mutation efficiency in wheat by optimizing gold particle size and heat treatment conditions.

bioRxiv · Apr 9, 2022 · PreprintPlant Biology

Impact of temperature and time on DNA-free Cas9-ribonucleoprotein mediated gene editing in wheat protoplasts and immature embryos

S. Poddar, J. Tanaka, K. L. D. Running, G. K. Kariyawasam, J. Faris, T. Friesen, M.-J. Cho, J. H. Cate, B. Staskawicz

This study improves DNA-free Cas9-RNP gene editing in wheat by optimizing temperature and time, achieving efficient gene knockouts without exogenous DNA.

bioRxiv · Apr 5, 2022Plant Biology

Efficient isolation of protoplasts from rice calli with pause points and its application in transient gene expression and genome editing assays

S. Poddar, J. Tanaka, J. H. D. Cate, B. Staskawicz, M.-J. Cho

This paper introduces a method for isolating rice protoplasts from calli with pause points, enabling flexible transfection and genome editing assays.

bioRxiv · Sep 1, 2020Plant Biology

Defective Nucleotide Catabolism Defines a Subset of Cancers Sensitive to Purine Nucleoside Phosphorylase Inhibition

E. R. Abt, V. Lok, T. M. Le, S. Poddar, W. Kim, J. R. Capri, G. Abril-Rodriguez, T. R. Donahue, J. Czernin, T. Mehrling, A. Ribas, C. G. Radu

This study identifies SAMHD1, dCK, and CDA as biomarkers for predicting sensitivity to PNP inhibitors in cancers, showing that PNP inhibition can target both hematological and solid tumors.

bioRxiv · Nov 4, 2019 · PreprintCancer Biology