Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice
P. Liu, S. Liang, C. Zheng, E. Mintzer, Y. G. Zhao, K. Ponnienselvan, A. Mir, E. J. Sontheimer, G. Gao, T. R. Flotte, S. Wolfe, W. Xue
This paper improves prime editors for genome editing in adult mice, enabling pathogenic mutation correction and cancer modeling.
Nature Communications · Apr 9, 2021Peer-reviewedBioengineering