CHCHD4 regulates a proliferation-EMT switch in tumour cells, through respiratory complex I mediated metabolism.
L. W. Thomas, C. Esposito, J. M. Stephen, A. S. Costa, C. Frezza, T. S. Blacker, G. Szabadkai, M. Ashcroft
This study shows CHCHD4 promotes tumour cell proliferation and suppresses EMT through complex I-mediated mitochondrial metabolism.
bioRxiv · Jan 7, 2019 · PreprintCell Biology