Author

A. S. Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

C. Frezza· 2 shared G. d. F. P. Rangel· 2 shared L. M. A. Rabelo· 2 shared R. F. d. C. Leitao· 2 shared A. Dugourd· 1 shared A. Erez· 1 shared A. F. Pereira· 1 shared A. G. Cajado· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

C. Frezza

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

McLTP1, a lipid transfer protein isolated from noni seeds induces effective healing of superficial burns

B. M. Kurita, G. d. F. P. Rangel, L. M. A. Rabelo, T. d. F. G. Souza, F. S. Macedo, R. F. d. C. Leitao, A. S. Costa, H. D. d. Oliveira, N. M. N. d. Alencar

This study investigates the effect of McLTP1, a lipid transfer protein from noni seeds, on superficial burn healing in mice, finding it promotes wound closure and reduces inflammation and oxidative stress.

bioRxiv · Feb 4, 2023 · PreprintImmunology

Uroprotective effect of a protein isolated from seed of Morinda citrifolia (McLTP1) on hemorrhagic cystitis induced by ifosfamide in mice

G. d. F. P. Rangel, A. G. Cajado, A. F. Pereira, L. M. A. Rabelo, A. S. Costa, H. D. de Oliveira, D. V. T. Wong, R. F. d. C. Leitao, R. C. P. Lima-Junior, N. M. N. de Alencar

This study evaluates the uroprotective effect of McLTP1, a protein from Morinda citrifolia seeds, in preventing ifosfamide-induced hemorrhagic cystitis in mice, showing reduced inflammation and oxidative stress.

bioRxiv · Jan 30, 2023 · PreprintPharmacology & Toxicology

Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progression

M. Sciacovelli, A. Dugourd, L. Valcarcel Jimenez, M. Yang, E. Nikitopoulou, A. S. Costa, L. Tronci, V. Caraffini, P. Rodrigues, C. Schmidt, D. G. Ryan, T. Young, V. Zecchini, S. H. Rossi, C. Massie, , C. Frezza

This study identifies metabolic reprogramming in renal cancer cells, showing how branched-chain amino acid catabolism and urea cycle enzymes support tumor progression and metastasis.

bioRxiv · Sep 17, 2021 · PreprintCancer Biology

CHCHD4 regulates a proliferation-EMT switch in tumour cells, through respiratory complex I mediated metabolism.

L. W. Thomas, C. Esposito, J. M. Stephen, A. S. Costa, C. Frezza, T. S. Blacker, G. Szabadkai, M. Ashcroft

This study shows CHCHD4 promotes tumour cell proliferation and suppresses EMT through complex I-mediated mitochondrial metabolism.

bioRxiv · Jan 7, 2019 · PreprintCell Biology