Author

T. S. Groth

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Chiang· 1 shared A. Szeglowski· 1 shared D. Guiggey· 1 shared I. T. Warren· 1 shared M. H. Maloy· 1 shared M. L. Yarmush· 1 shared N. Parashurama· 1 shared O. Ogoke· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

A. Chiang

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1 paper

Recent·Most cited

FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells

I. T. Warren, D. Guiggey, A. Chiang, M. H. Maloy, O. Ogoke, T. S. Groth, T. Mon, S. Meamardoost, X. Liu, S. Thompson, A. Szeglowski, R. Thompson, P. Chen, R. Paulmurugan, M. L. Yarmush, , N. Parashurama

This study shows that depletion of FOXA1/2 in human liver cells reprograms differentiation state and metabolism, promoting de-differentiation and pluripotency.

bioRxiv · Jun 1, 2020Bioengineering