Author

A. Chiang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

D. Guiggey· 2 shared E. M. Jordahl· 2 shared N. Parashurama· 2 shared O. Ogoke· 2 shared P. Chen· 2 shared R. W. Bowman· 2 shared S. Thompson· 2 shared A. F. O'Donnell· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

D. Guiggey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

α-Arrestins maintain phospholipid balance and Atg18 distribution to permit efficient autophagy

R. W. Bowman, S. Davis, E. M. Jordahl, K. Chera, N. Ozbaki-Yagan, J. Franks, S. Hawbaker, A. Chiang, O. Acar, D. Beer-Stoltz, A. F. ODonnell

This study identifies a role for α-arrestins in maintaining phospholipid balance and Atg18 distribution to support efficient autophagy.

bioRxiv · Aug 3, 2022 · PreprintCell Biology

Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturation

O. Ogoke, D. Guiggey, A. Chiang, S. Thompson, T. H. A. Nguyen, D. Berke, C. Ott, A. Kalinousky, C. Shamul, P. Chen, S. Ross, Z. Chen, P. Srivastava, C. Gaughan, S. D. Mahajan, , N. Parashurama

The paper links collective migration to differentiation in hPSC-derived hepatocytes, showing a significant increase in maturation through a deep-learning gene circuit.

bioRxiv · Jul 24, 2022 · PreprintBioengineering

Alpha-arrestins Aly1 and Aly2 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis

B. P. Robinson, S. E. Hawbaker, A. Chiang, E. M. Jordahl, S. Anaokar, A. Nikiforov, R. W. Bowman, P. Ziegler, C. K. McAtee, J. Patton-Vogt, A. F. O'Donnell

This paper shows that alpha-arrestins Aly1 and Aly2 regulate Git1 trafficking and phospholipid homeostasis in yeast by controlling Git1 localization and GPI metabolism.

bioRxiv · Feb 4, 2021Cell Biology

FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells

I. T. Warren, D. Guiggey, A. Chiang, M. H. Maloy, O. Ogoke, T. S. Groth, T. Mon, S. Meamardoost, X. Liu, S. Thompson, A. Szeglowski, R. Thompson, P. Chen, R. Paulmurugan, M. L. Yarmush, , N. Parashurama

This study shows that depletion of FOXA1/2 in human liver cells reprograms differentiation state and metabolism, promoting de-differentiation and pluripotency.

bioRxiv · Jun 1, 2020Bioengineering