Distinct transcriptional programs of SOX2 in different types of small cell lung cancers
Y. Tenjin, K. Matsuura, S. Kudoh, S. Usuki, T. Yamada, A. Matsuo, Y. Sato, H. Saito, K. Fujino, J. Wakimoto, T. Ichimura, H. Kohrogi, T. Sakagami, H. Niwa, T. Ito
This study identifies distinct SOX2 transcriptional programs in different SCLC subtypes and highlights the therapeutic potential of targeting the ASCL1-SOX2 axis in classical SCLC.
bioRxiv · Nov 28, 2019Cancer Biology