H. Saito

Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

This study shows that Tgif1 deficiency in osteoblasts disrupts cytoskeletal architecture by increasing PAK3 signaling, leading to impaired cell morphology, adherence, and migration.

Visualization of liquid-liquid phase transitions using a tiny G-quadruplex binding protein

The paper identifies SERF2 as a protein involved in stress granule formation and characterizes its interactions with G-quadruplex RNA structures to study liquid-liquid phase transitions.

Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability

This study shows that structural flexibility of A2-17 peptide enhances its ability to penetrate cell membranes compared to its constrained variants.

Monoterpene glucosides accumulated in Eustoma grandiflorum roots promote hyphal branching in arbuscular mycorrhizal fungi

Detecting and validating influential organisms for rice growth: An ecological network approach

The paper identifies influential organisms affecting rice growth using ecological network analysis and field experiments.

Hydroxylation site-specific and production-dependent roles of endogenous oxysterols in cellular cholesterol homeostasis

This study investigates how endogenously synthesized oxysterols regulate cholesterol homeostasis by affecting SREBP-2 and LXR, showing site-specific and production-dependent effects.

Tracheal motile cilia in mice require CAMSAP3 for formation of central microtubule pair and coordinated beating

This study shows CAMSAP3 is essential for forming the central microtubule pair in tracheal motile cilia and enabling coordinated beating in mice.

Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid

This study shows that c9,t11 CLA reduces amyloid-beta production in neurons by altering BACE1 and APP localization, potentially protecting against neurodegeneration.

Covering soybean leaves with cellulose nanofiber changes leaf surface hydrophobicity and confers resistance against Phakopsora pachyrhizi

This study shows that covering soybean leaves with cellulose nanofiber reduces disease severity caused by Phakopsora pachyrhizi by altering leaf hydrophobicity and suppressing pathogen-related gene expression.

Distinct transcriptional programs of SOX2 in different types of small cell lung cancers

This study identifies distinct SOX2 transcriptional programs in different SCLC subtypes and highlights the therapeutic potential of targeting the ASCL1-SOX2 axis in classical SCLC.