Author

T. Steinmetzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Hardes· 2 shared A. Pasquato· 1 shared A. Roulin· 1 shared C. Fedeli· 1 shared C. Rohde· 1 shared D. A. Stein· 1 shared D. B. Constam· 1 shared D. Bestle· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

K. Hardes

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets

D. Bestle, M. R. Heindl, H. Limburg, T. Van Lam van, O. Pilgram, H. Moulton, D. A. Stein, K. Hardes, M. Eickmann, O. Dolnik, C. Rohde, S. Becker, H.-D. Klenk, W. Garten, T. Steinmetzer, E. Bottcher-Friebertshauser

This study shows TMPRSS2 and furin are both critical for SARS-CoV-2 activation in human airway cells and that inhibiting them can effectively block virus replication.

bioRxiv · Apr 15, 2020 · PreprintMicrobiology

A novel cell-based sensor detecting the activity of individual basic proprotein convertases

K. I. Low, K. Hardes, C. Fedeli, N. G. Seidah, D. B. Constam, A. Pasquato, T. Steinmetzer, A. Roulin, S. Kunz

The paper introduces PCific, a cell-based sensor to screen and distinguish inhibitors of individual basic proprotein convertases in mammalian cells.

bioRxiv · Nov 6, 2018Biochemistry