T. Sugiki

Exploration of novel αβ-protein folds through de novo design

This study predicts and designs novel β-protein folds using topology rules, demonstrating their feasibility and suggesting a vast untapped space of possible folds.

Design of complicated all-α protein structures

This study designs complex all-α protein structures using helix-loop-helix motifs and canonical α-helices, achieving atomic accuracy and thermal stability in solution.