Gatekeeper helix activates Golgi SM protein Sly1 and directly mediates close-range vesicle tethering
M. Duan, R. L. Plemel, T. Takenaka, A. Lin, B. M. Delgado, U. Nattermann, D. P. Nickerson, J. Mima, E. A. Miller, A. J. Merz
The paper identifies a gatekeeper helix in Sly1 that binds membranes to relieve autoinhibition and mediate close-range vesicle tethering in the early secretory pathway.
bioRxiv · Jan 16, 2020 · PreprintCell Biology