Author

A. J. Merz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Organism:yeast· 3 Research Focus:cell type annotation· 2 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. L. Leveille· 2 shared M. Duan· 2 shared R. L. Plemel· 2 shared S. L. Keller· 2 shared A. Dosey· 1 shared A. Lin· 1 shared B. M. Delgado· 1 shared C. Cornell· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

C. L. Leveille

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Remodeling of yeast vacuole membrane lipidomes from the log (1-phase) to stationary stage (2-phases)

J. Reinhard, C. L. Leveille, C. Cornell, A. J. Merz, C. Klose, R. Ernst, S. L. Keller

This paper investigates lipid composition changes in yeast vacuole membranes during growth to quiescence, finding increased phosphatidylcholine with higher melting temperatures.

bioRxiv · Oct 11, 2022Biophysics

Yeast cells actively tune their membranes to phase separate at temperatures that scale with growth temperatures

C. L. Leveille, C. E. Cornell, A. J. Merz, S. L. Keller

This study shows yeast cells regulate vacuole membrane phase separation by adjusting ergosterol levels to maintain a temperature offset from their growth temperature.

bioRxiv · Sep 14, 2021Biophysics

Plate-based assay of Adaptor Protein 3 (AP-3) traffic in budding yeast

R. L. Plemel, G. Odorizzi, A. J. Merz

The paper introduces a synthetic reporter, GNSI, for assessing AP-3 function in budding yeast through plate-based assays and high-throughput screening.

bioRxiv · Dec 2, 2020 · PreprintCell Biology

Gatekeeper helix activates Golgi SM protein Sly1 and directly mediates close-range vesicle tethering

M. Duan, R. L. Plemel, T. Takenaka, A. Lin, B. M. Delgado, U. Nattermann, D. P. Nickerson, J. Mima, E. A. Miller, A. J. Merz

The paper identifies a gatekeeper helix in Sly1 that binds membranes to relieve autoinhibition and mediate close-range vesicle tethering in the early secretory pathway.

bioRxiv · Jan 16, 2020 · PreprintCell Biology

Golgi SM protein Sly1 promotes productive trans-SNARE complex assembly through multiple mechanisms

M. Duan, G. Gao, D. K. Banfield, A. J. Merz

The paper identifies three mechanisms by which Sly1 enhances SNARE-mediated membrane fusion and shows that close-range tethering is crucial when cis-SNARE assembly competes.

bioRxiv · Jan 16, 2020 · PreprintCell Biology

The Dense-Core Vesicle Maturation Protein CCCP-1 Binds RAB-2 and Membranes through its C-terminal Domain

J. Cattin-Ortola, I. Topalidou, A. Dosey, A. J. Merz, M. Ailion

This study identifies the C-terminal domain of CCCP-1 as essential for its localization, RAB-2 binding, membrane interaction, and role in DCV biogenesis.

bioRxiv · May 29, 2017Biochemistry