WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2
L. G. H. S. Aragao, J. T. Oliveira, J. R. Temerozo, M. A. Mendes, J. A. Salerno, C. d. S. G. Pedrosa, T. Puig-Pijuan, C. Verissimo, I. M. Ornelas, T. Torquato, G. Vitoria, C. Q. Sacramento, N. Fintelman-Rodrigues, S. d. S. G. Dias, V. Cardoso Soares, , S. Rehen
This study examines the effects of the cannabinoid agonist WIN 55,212-2 on inflammation and cell survival in human iPSC-derived cardiomyocytes infected with SARS-CoV-2, finding reduced cytokine levels and cytotoxic damage.
bioRxiv · Feb 20, 2021 · PreprintCell Biology