Author

K. Karmirian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

I. M. Ornelas· 3 shared J. A. Salerno· 3 shared L. Goto-Silva· 3 shared S. Rehen· 3 shared C. d. S. G. Pedrosa· 2 shared C. Q. Sacramento· 2 shared C. Verissimo· 2 shared D. Biagi· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

I. M. Ornelas

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Author profile →

3 papers

Recent·Most cited

Proteomic changes induced by harmine in human brain organoids reveal signaling pathways related to neuroprotection

K. Karmirian, L. Goto-Silva, J. M. Nascimento, M. N. Costa, J. A. Salerno, I. M. Ornelas, B. Vanderborght, D. Martins-de-Souza, S. Rehen

This study identifies proteomic changes in human brain organoids treated with harmine, revealing pathways linked to neuroprotection such as synaptic vesicle cycle and neurotrophin signaling.

bioRxiv · Jun 16, 2021 · PreprintCell Biology

WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2

L. G. H. S. Aragao, J. T. Oliveira, J. R. Temerozo, M. A. Mendes, J. A. Salerno, C. d. S. G. Pedrosa, T. Puig-Pijuan, C. Verissimo, I. M. Ornelas, T. Torquato, G. Vitoria, C. Q. Sacramento, N. Fintelman-Rodrigues, S. d. S. G. Dias, V. Cardoso Soares, , S. Rehen

This study examines the effects of the cannabinoid agonist WIN 55,212-2 on inflammation and cell survival in human iPSC-derived cardiomyocytes infected with SARS-CoV-2, finding reduced cytokine levels and cytotoxic damage.

bioRxiv · Feb 20, 2021 · PreprintCell Biology

Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility

J. A. Salerno, T. Torquato, J. R. Temerozo, L. Goto-Silva, M. A. Mendes, C. Q. Sacramento, N. Fintelman-Rodrigues, G. Vitoria, L. R. Q. Souza, I. M. Ornelas, C. Verissimo, K. Karmirian, C. d. S. G. Pedrosa, S. d. S. G. Dias, V. C. Soares, , S. Rehen

This study shows that inhibiting the Sigma-1 receptor with NE-100 reduces SARS-CoV-2 infection in human cardiomyocytes but also impairs cytoskeleton and contractility.

bioRxiv · Feb 20, 2021 · PreprintCell Biology