Author

I. M. Ornelas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. A. Salerno· 3 shared K. Karmirian· 3 shared L. Goto-Silva· 3 shared S. Rehen· 3 shared C. d. S. G. Pedrosa· 2 shared C. Q. Sacramento· 2 shared C. Verissimo· 2 shared D. Biagi· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCell Biology

J. A. Salerno

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 19, 2023

Systematic Characterization of LSD metabolites in C. elegans by ultra-high performance liquid chromatography coupled with high-resolution tandem mass spectrometry

C. M. d. V. Silveira, V. F. dos Santos, I. M. Ornelas…·M. Junqueira

This study identifies and quantifies LSD metabolites in C. elegans using UHPLC-HRMS/MS, revealing metabolic pathways and pharmacokinetics.

DOI 10.1101/2023.06.19.545563

C. elegansmetabolomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 16, 2021

Proteomic changes induced by harmine in human brain organoids reveal signaling pathways related to neuroprotection

K. Karmirian, L. Goto-Silva, J. M. Nascimento…·S. Rehen

This study identifies proteomic changes in human brain organoids treated with harmine, revealing pathways linked to neuroprotection such as synaptic vesicle cycle and neurotrophin signaling.

DOI 10.1101/2021.06.16.448740

humanproteomics

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Cell BiologybioRxivPreprintFeb 20, 2021

WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2

L. G. H. S. Aragao, J. T. Oliveira, J. R. Temerozo…·S. Rehen

This study examines the effects of the cannabinoid agonist WIN 55,212-2 on inflammation and cell survival in human iPSC-derived cardiomyocytes infected with SARS-CoV-2, finding reduced cytokine levels and cytotoxic damage.

DOI 10.1101/2021.02.20.431855

humanbulk RNA-seq

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Cell BiologybioRxivPreprintFeb 20, 2021

Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility

J. A. Salerno, T. Torquato, J. R. Temerozo…·S. Rehen

This study shows that inhibiting the Sigma-1 receptor with NE-100 reduces SARS-CoV-2 infection in human cardiomyocytes but also impairs cytoskeleton and contractility.

DOI 10.1101/2021.02.20.432092

humanexperimental assay

𝕏 PostBluesky