The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy
D. G. Broadbent, C. M. McEwan, T.-M. Tsang, D. M. Poole, B. C. Naylor, J. C. Price, J. C. Schmidt, J. L. Andersen
This study identifies poly-ubiquitin as a signal recruiting ATG9A to initiate basal autophagy by mediating autophagy foci assembly.
bioRxiv · Nov 28, 2023 · PreprintCell Biology