J. C. Price

The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy

This study identifies poly-ubiquitin as a signal recruiting ATG9A to initiate basal autophagy by mediating autophagy foci assembly.

Micrococcin cysteine-to-thiazole conversion through transient interactions between a scaffolding protein and two modification enzymes

The paper identifies key interactions in the enzymatic complex responsible for converting cysteine to thiazole in micrococcin biosynthesis, revealing a dynamic mechanism involving transient associations between scaffold and modifying enzymes.

Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway

This study visualizes the Cdc48 AAA+ ATPase unfolding pathway using structural snapshots, revealing a hand-over-hand mechanism and the sequential ATP hydrolysis and substrate interaction between D1 and D2 subunits.

Structural stability of Human serum albumin is modified in rheumatoid arthritis

This study uses differential scanning calorimetry and proteomics to show that human serum albumin has altered thermal stability in rheumatoid arthritis patients, potentially linked to changes in protein structure and interactions.

Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time

This paper introduces sandSTORM, a STORM variant using nanodiamonds for faster, less damaging super-resolution imaging with unlimited observation time.

Effect of PEI-coated MNPs on the Regulation of Cellular Focal Adhesions and Actin Stress Fibres

This study investigates how PEI-coated magnetic nanoparticles affect cell adhesion and stress fibre formation, finding dose-dependent increases in these processes and identifying a safe dosage to reduce toxicity.