PEG-Arginase 1: A Novel Therapy for Optic Nerve Injury
Mai Yamamoto, Syed Adeel H. Zaidi, Tahira Lemtalsi, Zhimin Xu, Porsche V. Sandow, Robert W. Caldwell, Ruth B. Caldwell, Modesto Rojas
This paper demonstrates that PEG-A1 treatment reduces retinal injury and preserves vision after optic nerve trauma by modulating the ornithine/polyamine pathway.
bioRxiv · Aug 27, 2026 · PreprintCell Biology