Ruth B. Caldwell

This paper demonstrates that PEG-A1 treatment reduces retinal injury and preserves vision after optic nerve trauma by modulating the ornithine/polyamine pathway.

Inhibiting cholesterol esterification limits retinal neurovascular injury in diabetes.

This study shows that CTR1 contributes to retinal ischemia-reperfusion injury by promoting oxidative stress and inflammation, and that copper chelators like TTM can mitigate these effects.

This study shows that loss of neurofibromin activates GLUT1 in macrophages, leading to increased glycolysis and retinal neovascularization in NF1 mice.