Author

Takuto Sato

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:Bayesian inference· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Andrew Bernier· 1 shared April Jung· 1 shared Bharathi Gandi· 1 shared Brendan S. Blumenstiel· 1 shared Chip StewartiD· 1 shared Corey NoletiD· 1 shared Dan Mazur· 1 shared David I. Benjamin· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Andrew Bernier

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cost-efficient whole genome-sequencing using novel mostly natural sequencing-by-synthesis chemistry and open fluidics platform

Gilad Almogy, Mark Pratt, Florian C. Oberstrass, Linda Lee, Dan Mazur, Nate Beckett, Omer Barad, Ilya Soifer, Eddie Perelman, Yoav Etzioni, Martin Sosa, April Jung, Tyson A. Clark, Eliane H. Trepagnier, Gila Lithwick‐Yanai, , Doron Lipson

Open flow cell on a circular wafer with mostly natural nucleotides and no reversible terminators: about 300 bp reads at $1/Gb, 99.6% SNP accuracy on reference human genomes.

bioRxiv · May 29, 2022 · PreprintGenomics

Calling Somatic SNVs and Indels with Mutect2

David I. Benjamin, Takuto Sato, Kristian Cibulskis, Gad A. Getz, Chip Stewart, Lee Lichtenstein

Mutect2 calls somatic SNVs and indels via local haplotype assembly, Bayesian genotyping and F-score-optimised filtering, with roughly one false call per 5 Mb in exome replicate-versus-replicate tests.

bioRxiv · Dec 2, 2019 · PreprintBioinformatics✦ In-depth digest