Author

Tamara Mclennan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adil S. al Hinai· 1 shared Andrew W. Roberts· 1 shared Annelieke Zeilemaker· 1 shared Ashish Bajel· 1 shared Bob Löwenberg· 1 shared Bram Luiken· 1 shared Christoffer FlensburgiD· 1 shared Edward ChewiD· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adil S. al Hinai

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1 paper

Recent·Most cited

Germline loss of MBD4 predisposes to leukaemia due to a mutagenic cascade driven by 5mC

Mathijs A. Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E. Miller, Adil S. al Hinai, Ashish Bajel, Bram Luiken, Melissa Rijken, Tamara Mclennan, Remco M. Hoogenboezem, François G. Kavelaars, Marnie E. Blewitt, Eric M. Bindels, Warren S. Alexander, , Ian J. Majewski

This study shows that germline MBD4 loss causes AML with high C>T mutations due to 5mC deamination, and highlights interactions with somatic DNMT3A mutations.

bioRxiv · Nov 1, 2017 · PreprintCancer Biology