Author

Warren S. Alexander

Primary ORCID profile (0000-0002-1824-7701 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Warren S. AlexanderiD1 paper · The University of Melbourne

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew W. Roberts· 2 shared Christoffer FlensburgiD· 2 shared Ian J. MajewskiiD· 2 shared Adil S. al Hinai· 1 shared Annelieke Zeilemaker· 1 shared Ashish Bajel· 1 shared Astrid Bosma· 1 shared Bob Löwenberg· 1 shared

Activity by Year

2017-2017 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Andrew W. Roberts

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Author profile →

2 papers

Recent·Most cited

Germline loss of MBD4 predisposes to leukaemia due to a mutagenic cascade driven by 5mC

Mathijs A. Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E. Miller, Adil S. al Hinai, Ashish Bajel, Bram Luiken, Melissa Rijken, Tamara Mclennan, Remco M. Hoogenboezem, François G. Kavelaars, Marnie E. Blewitt, Eric M. Bindels, Warren S. Alexander, , Ian J. Majewski

This study shows that germline MBD4 loss causes AML with high C>T mutations due to 5mC deamination, and highlights interactions with somatic DNMT3A mutations.

bioRxiv · Nov 1, 2017 · PreprintCancer Biology

Dynamic changes in clonal architecture during disease progression in follicular lymphoma

Christoffer Flensburg, Tobias Sargeant, Astrid Bosma, Roelof J. C. Kluin, Robby E. Kibbelaar, Mels Hoogendoorn, Warren S. Alexander, Andrew W. Roberts, René Bernards, Daphne de Jong, Ian J. Majewski

This study analyzes DNA and RNA sequencing data from follicular lymphoma patients to identify mutations and transcriptional changes during transformation to diffuse large B cell lymphoma.

bioRxiv · Sep 11, 2017 · PreprintCancer Biology