Macrophages redeploy functional cancer cell surface proteins following phagocytosis
Regan F. Volk, Sara E. Casebeer, Andrew C Condon, Bahar Zirak, Nayelis A. Manon, Iryna Irkliyenko, Huajun Liao, Tao Shao, Tommaso Pollini, Vijay Ramani, Ajay V. Maker, Trevor P. Fidler, Hani Goodarzi, Balyn W. Zaro
This study shows that macrophages transfer intact cancer cell surface proteins to their own surface after phagocytosis, which may affect their function and metabolism.
bioRxiv · Sep 23, 2024 · PreprintImmunology