Author

Sara E. Casebeer

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Balyn W. ZaroiD· 2 shared Regan F. VolkiD· 2 shared Ajay V. MakeriD· 1 shared Andrew C Condon· 1 shared Anne L. SapiroiD· 1 shared Bahar Zirak· 1 shared Beth M. HayesiD· 1 shared Brandon Hochahn LeeiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Balyn W. ZaroORCID

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2 papers

Recent·Most cited

Macrophages redeploy functional cancer cell surface proteins following phagocytosis

Regan F. Volk, Sara E. Casebeer, Andrew C Condon, Bahar Zirak, Nayelis A. Manon, Iryna Irkliyenko, Huajun Liao, Tao Shao, Tommaso Pollini, Vijay Ramani, Ajay V. Maker, Trevor P. Fidler, Hani Goodarzi, Balyn W. Zaro

This study shows that macrophages transfer intact cancer cell surface proteins to their own surface after phagocytosis, which may affect their function and metabolism.

bioRxiv · Sep 23, 2024 · PreprintImmunology

P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by Borrelia burgdorferi

Michal Caspi Tal, Paige S. Hansen, Haley A. Ogasawara, Qingying Feng, Regan F. Volk, Brandon Hochahn Lee, Sara E. Casebeer, Grace Blacker, Maia Shoham, Sarah Galloway, Anne L. Sapiro, Beth M. Hayes, Laughing Bear Torrez Dulgeroff, Tal Raveh, Venkata Raveendra Pothineni, , Balyn W. Zaro

This study identifies P66, a bacterial protein mimicking CD47, which binds SIRPα to evade macrophage phagocytosis, and shows its role in Lyme Disease pathogenesis.

bioRxiv · Apr 29, 2024 · PreprintImmunology