Integrated single cell analysis reveals co-evolution of malignant B cells and the tumor microenvironment in transformed follicular lymphoma
Clémentine Sarkozy, Shaocheng Wu, Katsuyoshi Takata, Tomohiro Aoki, Susana Ben Neriah, Katy Milne, Talia Goodyear, Celia Strong, Tashi Rastogi, Daniel Lai, Laurie Helen Sehn, Pedro Farinha, Brad H. Nelson, Andrew P. Weng, David W. Scott, , Andrew J. L. Roth
The paper uses single-cell sequencing to study the evolution of follicular lymphoma and its microenvironment during transformation, finding gene programs and TME changes associated with progression.
bioRxiv · Nov 17, 2022 · PreprintBioinformatics