Molecular BiologybioRxivPreprint
Loss of Pigment Epithelium Derived Factor Sensitizes C57BL/6J Mice to Light-Induced Retinal Damage
Debresha A. Shelton, Jack T. Papania, Tatiana E. Getz…·John M. Nickerson
This study shows that PEDF deficiency in mice increases light-induced retinal damage, with worsened visual function, retinal thinning, and Galectin-3 expression.