Distinctive cross-ancestry genetic architecture for age-related macular degeneration
Bryan R. Gorman, Georgios Voloudakis, Robert P. Igo, Tyler G. Kinzy, Christopher W. Halladay, Tim B. Bigdeli, Biao Zeng, Sanan Venkatesh, Jessica N. Cooke Bailey, Dana C. Crawford, Kyriacos Markianos, Frederick N. Dong, Patrick A. Schreiner, Wen Zhang, VA Million Veteran Program, , Srinivas V. Goverdhan
This study identifies 63 AMD risk loci across multiple ancestries, highlighting ancestry-dependent genetic heterogeneity and potential therapeutic targets.
Nature Genetics · Dec 1, 2024Peer-reviewedGenetic & Genomic Medicine