Cadherins modulate the self-organizing potential of gastruloids
Alexandre Mayran, Dominique Kolly, Lucille Lopez‐Delisle, Yuliia Romaniuk, Maxine Leonardi, Anne-Catherine Cossy, Theo Lacroix, Ana Rita Amândio, Pierre Osteil, Denis Duboule
This study identifies a Cadherin switch mechanism that regulates self-organization in gastruloids by linking pluripotency exit and cell differentiation.
bioRxiv · Nov 22, 2023 · PreprintDevelopmental Biology