Developmental BiologyNature CommunicationsPeer-reviewed
Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues
Nathaniel R. Kastan, Ksenia Gnedeva, Theresa Alisch…·Albert James Hudspeth
The paper identifies a small-molecule inhibitor of Lats kinases that promotes Yap-dependent proliferation in postmitotic mammalian tissues, enabling hair cell regeneration in the inner ear.