Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24
Xiongwen Cao, Alexandra Khitun, Yang Luo, Zhenkun Na, Thitima Phoodokmai, Khomkrit Sappakhaw, Elizabeth Olatunji, Chayasith Uttamapinant, Sarah A. Slavoff
The paper identifies alt-RPL36 as a novel regulator of PI3K-AKT-mTOR signaling through interaction with TMEM24, showing its role in modulating PI(4,5)P2 levels and cell size.
Nature Communications · Jan 21, 2021Peer-reviewedGenomics