Alexandra Khitun

This paper presents a scaffold strategy to improve cryo-EM resolution for small RNAs, demonstrating high-resolution structures of a TPP riboswitch and its ligand binding dynamics.

This study maps RNA translation dynamics in the human brain using ribosome profiling, identifying thousands of novel translation events and brain-specific microproteins linked to schizophrenia.

The paper identifies nascent alternative proteins in human cells using chemoproteomics and shows one represses ribosome biogenesis.

The paper identifies alt-RPL36 as a novel regulator of PI3K-AKT-mTOR signaling through interaction with TMEM24, showing its role in modulating PI(4,5)P2 levels and cell size.