Author

Thomas C. Brook

University of Westminster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:metagenomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Lesley HoylesiD· 2 shared Lindsay J. HalliD· 2 shared Magdalena KujawskaiD· 2 shared Anne L. McCartneyiD· 1 shared Cristina Alcon-Giner· 1 shared Darren HeavensiD· 1 shared David NegusiD· 1 shared Fiona NewberryiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Lesley HoylesORCID

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2 papers

Recent·Most cited

Weberviruses are gut-associated phages that infect Klebsiella spp.

Samuel Dawson, Preetha Shibu, Sara Garnett, Fiona Newberry, Thomas C. Brook, Tobi Tijani, Magdalena Kujawska, Lindsay J. Hall, Anne L. McCartney, David Negus, Lesley Hoyles

The paper identifies and characterizes seven new lytic phages infecting Klebsiella, confirms their classification as Webervirus, and identifies a new genus, while highlighting their potential as therapeutic agents against multidrug-resistant strains.

FEMS Microbiology Ecology · Apr 14, 2025Peer-reviewedMicrobiology

Rapid profiling of the preterm infant gut microbiota using nanopore sequencing aids pathogen diagnostics

Richard M. Leggett, Cristina Alcon-Giner, Darren Heavens, Shabhonam Caim, Thomas C. Brook, Magdalena Kujawska, Samuel Martin, Ned Peel, Holly Acford-Palmer, Lesley Hoyles, Paul Clarke, Lindsay J. Hall, Matthew D. Clark

This study uses nanopore sequencing to rapidly profile preterm infant gut microbiota, enabling pathogen detection and antimicrobial resistance profiling within one hour.

Nature Microbiology · Dec 16, 2019Peer-reviewedGenomics