Richard M. Leggett

This study uses airborne DNA metagenomics to monitor biodiversity across time and space, revealing seasonal and spatial shifts in species composition.

This study uses long-read metagenomics to analyze the microbiome and resistome in advanced chronic liver disease, identifying Enterococcus faecium dominance and resistance gene enrichment linked to disease severity.

MARTi provides real-time metagenomic analysis and visualization using open-source tools, supporting classification methods like BLAST and Kraken2 for taxonomic and AMR gene identification.

The paper evaluates nanopore sequencing and assembly improvements for Arabidopsis genome assembly and methylation analysis using a single MinION flow cell.

MetaCortex improves metagenomic assembly by capturing intra-species diversity, achieving higher coverage and contiguity in simulated and mock communities.

The paper introduces Air-seq, a method to monitor agricultural ecosystem biodiversity using airborne DNA, showing it can detect pathogens and track their abundance over time.

This paper demonstrates how adaptive sampling in nanopore sequencing can enrich low-abundance species in metagenomic samples, with efficiency improving with longer read lengths and a mathematical model to predict outcomes.

This paper demonstrates a low-input DNA extraction and library preparation method for nanopore sequencing, enabling rapid de novo genome assembly from minimal DNA samples.

Alvis visualizes alignments and detects chimeric reads to improve assembly contiguity.

This study uses nanopore sequencing to rapidly profile preterm infant gut microbiota, enabling pathogen detection and antimicrobial resistance profiling within one hour.