Lindsay J. Hall

This study shows that Bacteroides thetaiotaomicron-derived extracellular vesicles inhibit melanoma growth via immune activation rather than direct cytotoxicity.

This study uses long-read metagenomics to analyze the microbiome and resistome in advanced chronic liver disease, identifying Enterococcus faecium dominance and resistance gene enrichment linked to disease severity.

This paper shows that Bifidobacterium pseudocatenulatum extracellular vesicles reduce melanoma growth by promoting Ly6G+ granulocyte infiltration through TLR2 activation.

The paper identifies a CD87-dependent coagulation pathway that enhances Th17 potential in neonatal cDC2, with implications for early-life immunity.

The paper identifies a novel gene cluster in Bifidobacterium pseudolongum that enables resistant starch utilization, linking CAZyme profiles to niche adaptation in infant and adult microbiomes.

This study analyzes the population genomics of Staphylococcus haemolyticus to understand its transition from commensal to pathogenic states.

This study analyzes prophages and defense systems in Bifidobacterium genomes to reveal co-evolutionary 'arms race' dynamics between bacteria and phages.

This study identifies host-specific genomic and microbiome adaptations in Bifidobacterium across diverse animal hosts, revealing co-evolutionary dynamics and functional traits shaped by diet and phylogeny.

This study examines how early antibiotic and probiotic treatments affect the gut microbiome and resistome in preterm infants, finding that probiotics reduce antibiotic resistance genes and MDR pathogens but do not eliminate them.

This study identifies PNGaseL from Flavobacterium akiainvivens as an enzyme with broad N-glycan specificity, outperforming PNGaseF and PNGaseA in cleaving diverse glycan structures.

This study identifies Staphylococcus haemolyticus as a common gut colonizer in preterm infants and reveals its role as a reservoir of antibiotic resistance genes through genomic analysis.

The paper identifies and characterizes seven new lytic phages infecting Klebsiella, confirms their classification as Webervirus, and identifies a new genus, while highlighting their potential as therapeutic agents against multidrug-resistant strains.

The paper shows that Escherichia coli and Bifidobacterium bifidum have a mutualistic interaction in degrading human milk oligosaccharides in healthy infants.

The paper identifies Clostridium species that metabolize human milk oligosaccharides, producing beneficial metabolites and suppressing inflammation and pathogen growth in preterm infants.

This study shows that Bifidobacterium pseudocatenulatum 210 EPS enhances anti-tumour immunity and improves cancer therapy responses in pre-clinical models.

This study shows that infant gut microbiota at 1 month are most responsive to dietary changes, while 18-month-olds show resilience, with formula affecting fewer metabolic pathways than breast milk.

This study shows that maternal colonization with Bifidobacterium breve during pregnancy alters fetal brain metabolism and expression of key pathways.

The paper describes an optimized DNA extraction method for skin swabs suitable for shotgun metagenomics, validated on adult and baby samples to characterize bacterial microbiota effectively.

This study uses nanopore sequencing to rapidly profile preterm infant gut microbiota, enabling pathogen detection and antimicrobial resistance profiling within one hour.

The paper uses transcriptomics and network analysis to study regulatory networks in Paneth and goblet cell enriched gut organoids, identifying key regulators and their links to inflammatory bowel disease.

The paper introduces a method for rapid microbiome analytics using streaming histogram sketches, enabling efficient classification and similarity searches of microbiome data.

The paper integrates proteomic and transcriptomic data from intestinal organoids to identify autophagy-dependent processes in Paneth cells, showing that autophagy impairment affects protein abundance and key cellular functions.