Author

Thomas N. O’Connell

Pfizer (United States)

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Molecular Biology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

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Aiping DongiD· 1 shared Aliakbar Khalili Yazdi· 1 shared C.H. ArrowsmithiD· 1 shared Caroline Schild‐PoulteriD· 1 shared Chakrapani SubramanyamiD· 1 shared Cong DongiD· 1 shared Dafydd R. OweniD· 1 shared Dalia Baršytė-LovejoyiD· 1 shared

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1 paper

Recent·Most cited

Molecular BiologyNature Chemical BiologyPeer-reviewedMay 21, 2024

A chemical probe to modulate human GID4 Pro/N-degron interactions

Dominic D. G. Owens, Matthew E. R. Maitland, Aliakbar Khalili Yazdi…·C.H. Arrowsmith

The paper introduces PFI-7, a chemical probe that inhibits GID4 Pro/N-degron interactions, revealing non-degradative roles of the CTLH complex in human cells.

41 citationstop 3%

humanproteomics

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