Author
Pfizer (United States)ORCID 0000-0003-3106-7809Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Xiaoyun Wang, Jianxian Sun, Shabbir Ahmad…·Levon Halabelian
This study introduces E-ASMS, a method to detect weak binders and assess enantioselectivity, identifying 16 binders across 12 human protein targets with confirmed binding mechanisms.
Dominic D. G. Owens, Matthew E. R. Maitland, Aliakbar Khalili Yazdi…·C.H. Arrowsmith
The paper introduces PFI-7, a chemical probe that inhibits GID4 Pro/N-degron interactions, revealing non-degradative roles of the CTLH complex in human cells.
Daniel Conole, Fangyuan Cao, Christopher W. am Ende…·Edward W. Tate
The paper identifies a small molecule DUB probe, IMP-2373, that quantitatively engages multiple DUBs in live cells and demonstrates its use in studying DUB activity changes during MYC deregulation.