Author

Thomas Sparsø

Novo Nordisk (Denmark)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Amy Hauck NewmaniD· 1 shared Dmitry Kuznetsov· 1 shared Freja HerborgiD· 1 shared Henrik Berg RasmusseniD· 1 shared Iulian Dragan· 1 shared Jonatan Fullerton StøieriD· 1 shared Mark R. IbbersoniD· 1 shared Randy BlakelyiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Amy Hauck NewmanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Disruptive mutations in the serotonin transporter associate serotonin dysfunction with treatment-resistant affective disorder

Jonatan Fullerton Støier, Trine Nygaard Jørgensen, Thomas Sparsø, Henrik Berg Rasmussen, Vivek Kumar, Amy Hauck Newman, Randy Blakely, Thomas Mears Werge, Ulrik Gether, Freja Herborg

The paper identifies two disruptive SERT variants in treatment-resistant affective disorder patients and shows they cause partial loss-of-function, with one variant responsive to pharmacochaperoning.

medRxiv · Aug 29, 2023 · PreprintGenetic & Genomic Medicine

dsSwissKnife: An R package for federated data analysis

Iulian Dragan, Thomas Sparsø, Dmitry Kuznetsov, Roderick C. Slieker, Mark R. Ibberson

dsSwissKnife enables federated data analysis in R, supporting biomarker discovery across harmonized datasets from multiple observational cohorts.

bioRxiv · Nov 17, 2020 · PreprintBioinformatics