Jonatan Fullerton Støier

The paper identifies two disruptive SERT variants in treatment-resistant affective disorder patients and shows they cause partial loss-of-function, with one variant responsive to pharmacochaperoning.

The paper uses super-resolution microscopy to show that dopamine transporter (DAT) in neurons exists in dynamic nanodomain and unclustered configurations, regulated by excitatory drive and D2-autoreceptor activity.

This paper introduces a method to detect dopamine using genetically encoded fluorescent sensors in vitro and ex vivo, demonstrating its application for measuring dopamine release, uptake, and efflux.