Dual SMAD inhibition and Wnt inhibition enhances the differentiation of induced pluripotent stem cells into Retinal Ganglion cells (iPSC-RGCs)
Venkata Ramana Murthy Chavali, Naqi Haider, Sonika Rathi, Vrathasha Vrathasha, Teja R. Alapati, Jie He, Kamaljot Gill, Roman Nikonov, Thu T. Duong, Devin S. McDougald, Sergei S. Nikonov, Joan M. O’Brien, Jason A. Mills
This study develops a reproducible method to differentiate iPSCs into RGCs with high purity using dual SMAD and Wnt pathway inhibition.
Scientific Reports · Jul 16, 2020Peer-reviewedNeuroscience