Author

Roman Nikonov

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Ana Ripolles‐GarciaiD· 1 shared Artur V. CideciyaniD· 1 shared Devin S. McDougaldiD· 1 shared Gustavo David AguirreiD· 1 shared Jason A. MillsiD· 1 shared Jie HeiD· 1 shared Joan M. O’BrieniD· 1 shared Kamaljot GilliD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Ana Ripolles‐GarciaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Gene Therapy Reforms Photoreceptor Structure and Restores Vision in NPHP5-associated Leber Congenital Amaurosis

Gustavo David Aguirre, Artur V. Cideciyan, Valérie Dufour, Ana Ripolles‐Garcia, Raghavi Sudharsan, Małgorzata Świder, Roman Nikonov, Simone Iwabe, Sanford L. Boye, William W. Hauswirth, Samuel G. Jacobson, William A. Beltran

This paper demonstrates that gene therapy using AAV-mediated NPHP5 augmentation restores photoreceptor structure and function in a canine model of Leber congenital amaurosis.

Molecular Therapy · Mar 27, 2021Peer-reviewedNeuroscience

Dual SMAD inhibition and Wnt inhibition enhances the differentiation of induced pluripotent stem cells into Retinal Ganglion cells (iPSC-RGCs)

Venkata Ramana Murthy Chavali, Naqi Haider, Sonika Rathi, Vrathasha Vrathasha, Teja R. Alapati, Jie He, Kamaljot Gill, Roman Nikonov, Thu T. Duong, Devin S. McDougald, Sergei S. Nikonov, Joan M. O’Brien, Jason A. Mills

This study develops a reproducible method to differentiate iPSCs into RGCs with high purity using dual SMAD and Wnt pathway inhibition.

Scientific Reports · Jul 16, 2020Peer-reviewedNeuroscience